PO-0846: Bowel dose-volume relationship for patientreported acute intestinal toxicity from pelvic IMRT

Three-dimensional gel dosimetry for dose volume histogram verification in compensator-based IMRT

Background: Some tissues in human body are radiobiologically different from water and these inhomogeneity must be considered in dose calculation in order to achieve an accurate dose delivery. Dose verification in complex radiation therapy techniques, such as intensity‐modulated radiation therapy (IMRT) calls for volumetric, tissue equivalent and energy independent dosimeter. The purpose of this...

Does Intensity Modulated Radiation Therapy (IMRT) prevent additional toxicity of treating the pelvic lymph nodes compared to treatment of the prostate only?

BACKGROUND To evaluate the risk of rectal, bladder and small bowel toxicity in intensity modulated radiation therapy (IMRT) of the prostate only compared to additional irradiation of the pelvic lymphatic region. METHODS For ten patients with localized prostate cancer, IMRT plans with a simultaneous integrated boost (SIB) were generated for treatment of the prostate only (plan-PO) and for addi...

Bowel-sparing intensity-modulated radiotherapy (IMRT) for palliation of large-volume pelvic bone metastases: rationale, technique and clinical implementation.

A prospective comparison of acute intestinal toxicity following whole pelvic versus small field intensity-modulated radiotherapy for prostate cancer

PURPOSE To compare the acute intestinal toxicity of whole pelvic (WP) and small field (SF) intensity-modulated radiotherapy (IMRT) for prostate cancer using dosimetric and metabolic parameters as well as clinical findings. METHODS Patients who received IMRT in either a definitive or postoperative setting were prospectively enrolled. Target volume and organs at risk including intestinal cavity...

Late small bowel toxicity after aggressive abdominopelvic intensity modulated radiation therapy

Purpose We retrospectively analyzed late small bowel toxicity in patients who received abdominal or pelvic intensity modulated radiation therapy (IMRT) to the small bowel with a maximum dose greater than the generally accepted maximal tolerable dose of 45 Gy. Methods and materials All patients (N = 94) who received IMRT with a point dose of at least 45 Gy to tightly contoured small bowel betw...